BP Americas, Inc. Biosciences Center Enzymologist in San Diego, California


Job title:

Biosciences Center Enzymologist


Corporate & Functions

Role synopsis:

The biological sciences are strategically important, growing in capability, and possibly disruptive to BP’s business model. BP established a Biosciences Center (BSC) to maintain critical mass in biosciences capability, to perfect current opportunities, and to assess future opportunities across the range of BP’s businesses. The Center is closely connected to BP businesses and external technologies to ensure the expertise required to progress opportunities through the early stages of technology development and to advise businesses on biological issues and partnership opportunities. The Center operates similarly to a start-up company, and requires a team made up of flexible, multi-skilled, innovative members that can work collaboratively across the research portfolio.

  • The Job is for an enzymologist or protein engineer, skilled in the art of protein design, who can take lead enzymes or de novo sequences and optimize them for better performance. They will provide expertise in enzyme kinetics, enzyme assays and enzyme development, including enzyme structure/function, across multiple platforms for the development of enzymes of interest.

  • As a Enzymologist for the BSC Science team, the initial focus of research activities will be on:

  1. Support of programs through enzyme discovery, enzyme improvement, and biochemical assay development and execution. The Enzymologist will also play a central role in highlighting bottlenecks in enzymatic processes and contribute to the Center’s development goals.

  2. Enzymological and biochemical support for the fermentation organism development program to produce a biologically-derived monomer for the production of polymers from glucose.

  3. Exploratory research programs focused on projects geared towards finding value-added opportunities for BP’s core business strategies.

The individual will join a group of interactive scientists and should have strong communication skills and demonstrated outstanding inter-disciplinary problem solving and scientific analytical skills, with a strong interest in the pursuit of scientific discovery. There will be opportunities for leadership development focused in key project areas. This position requires hands on work at the bench in the Center’s laboratory and/or at partner facilities with a recent history of delivering experimental results.

Req ID:



United States - California - San Diego

Is this a part time position?:


Relocation available:

Yes - Domestic (In country) only

Travel required:

Yes - up to 25%

Key accountabilities:

  • Serve as a technical expert in biocatalysis and maintain a deep scientific understanding of relevant disciplines such as computational and experimental enzymology.

  • Serve as a subject matter expert for enzymology and biochemical pathways and be familiar with enzyme cofactors, mechanistic pathways, and enzyme kinetics and stability for the improvement of enzyme activity.

  • Have working level understanding of chemistry and collaborate with the wider science team to integrate biological science with chemistry and catalysis to create novel business propositions for BP’s petrochemicals business as well as in service of other exploratory work.

Essential Education:

Education: PhD (Enzymology, Biochemistry, Chemical Biology, Bioorganic Chemistry or related computational science field)

Desirable criteria and qualifications:

  • Experience working with academic or 3rd party partners

  • Understanding of the scale-up of processes from lab scale to pilot scale

  • Demonstrated experience at executing changes to existing laboratory set-ups through appropriate use of management of change processes

  • Experience in simulating enzyme reactions or modelling enzyme activity

  • Experience with immobilized enzymes, high throughput screening and hits-to-leads, and assay automation

  • Experience with de novo enzyme design

  • Knowledge of carbohydrate chemistry and carbohydrate biochemical pathways

  • Experience with LC-MS, GC-MS, HPLC, and advanced analytical methods

About BP:

Our business is the exploration, production, refining, trading and distribution of energy. This is what we do, and we do it on a truly global scale. BP operates with business activities and customers in more than 80 countries across six continents. Every day, we serve millions of customers around the world. We are continually looking for talented, committed and ambitious people to help us shape the face of energy for the future.

The Research and Technology team is part of the Group Chief of Staff office. The role of Research & Technology inside BP is twofold: to provide leadership and oversight for Technology across BP; and to lead Research & Development (R&D) in emerging areas and in support of corporate renewal.

Application close date:




Job category:

Research & Technology

Countries (State/Region):

United States - California


If you are selected for a position in the United States, your employment will be contingent upon submission to and successful completion of a post-offer/pre-placement drug test (and alcohol screening/medical examination if required by the role) as well as pre-placement verification of the information and qualifications provided during the selection process. The drug screen requires a hair test for which BP must be able to obtain a sufficient hair sample for analysis (4 cm/1 ½” scalp, or > 2 cm/¾” body – arms & armpits/legs/chest)

As part of our dedication to the diversity of our workforce, BP is committed to Equal Employment Opportunity. Applicants will receive consideration for employment without regard for race, color, gender, religion, national origin, disability, veteran status, military status, age, marital status, sexual orientation, gender identity, genetic information or any other protected group status. We are also committed to providing reasonable accommodations for qualified individuals with disabilities and disabled veterans in our job application procedures. If you need assistance or an accommodation due to a disability, you may contact us or have one of your representatives contact us at BPUSApplicationAssis@bp.com or by telephone at 281.366.1999.

Read the Equal Employment Opportunity is the Law poster and the poster supplement - for more information about Equal Employment Opportunities. ( Spanish version )

BP is an equal employment opportunity and affirmative action employer. View our policy statement .

Essential experience and job requirements:

  • A minimum of 2-5 years of post-doctoral and/or industrial research, and enzyme development experience. Experience must be proven by a solid track record of publications and/or patents.

  • A high level of technical knowledge and skills in a broad range of enzymology-related fields including biochemical pathways, computational and rational protein design/folding (familiar with Rosetta or similar software), enzyme mechanism/kinetics, complex assay development, and protein expression / purification / characterization.

  • Ability to provide expert advice and innovation to develop solutions to complex technical issues

  • Project and program management skills with the ability to prioritize multiple demands and work successfully in a fast-paced and, at times, ambiguous environment.

  • Ability to plan and organize resources, design and execute experiments/programs independently, and interpret data from multiple sources

  • Motivated and in possession of excellent interpersonal skills, can communicate well within and between teams and be able to work to tight deadlines

  • Ability to prioritize responsibilities and work effectively in a multi-tasking and matrix-based environment

  • Experience participating in and/or leading small research work teams

  • Experience in project strategy development and implementation, including the development of intellectual property

  • Experience working with metabolically engineered microbial strains.

  • Demonstrated commitment to safety in the job environment

  • Exhibition of strong One Team behaviors.

Other Requirements (eg Travel, Location):

There are no additional requirements. Please respond with N/A below.

Eligibility Requirements:

If you are applying for a position in the United States, you must be at least 18 years of age, legally authorized to work in the United States; and not require sponsorship for employment visa status (e.g., TN, H1B status), now or in the future.